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Qiagen EZ1 Advanced XL for Nucleic Acid Purification


EZ1 Advanced XL systems provide a fully automatic functionality and eliminate a lot of tedious work for the users. These are suitable for a wide range of throughput requirements from low to medium.

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Qiagen EZ1 Advanced XL Category:


EZ1 Advanced XL performs automated nucleic acid purification for a wide range of sample types relevant for molecular diagnostics, human identity testing, forensics, biomedical research, and gene expression analysis.

Nucleic acid extraction and purification are useful for different purposes like molecular diagnosis, biomedical research, genetic identity testing, gene expression analysis, and forensics. The whole process of purification becomes easy when we combine convenient instruments with flexible protocols and an ergonomic setup.

. The EZ1 Advanced XL meets laboratory demands for an easy-to-use solution for high-quality nucleic acid purification that enables throughput of 14 samples in 20 minutes.”

Qiagen follows this idea and designed several systems for nucleic acid purification. One such model is the EZ1 Advanced XL. There is another similar model with the name EZ1 Advanced but, the former is a better version of the latter. Have a look at this system’s specifications, features, and specialties.

EZ1 Advanced XL Systems: 

The EZ1 Advanced XL systems provide a fully automatic functionality and eliminate a lot of tedious work for the users. These are suitable for a wide range of throughput requirements from low to medium. Operators can cascade and connect around 4 of the Advanced systems to a computer for enhanced performances.


  • Size/ Dimensions – 51 x 51 x 57 cm
  • Pipetting Range – 50 – 1000 micro-ml
  • Weight – 48 Kg
  • Throughput – 1-14 samples for each run
  • Power – 100-240 V AC

Features and Benefits: 

The EZ1 Advanced XL systems are highly self-contained and provide several operational advantages. These systems help handle urgent samples for daily testing or long-term researches. The following features of these systems account for versatile downstream applications in the present day. Have a look.

1. Simple Usage: 

Qiagen designed these systems such that they are convenient and easy to use. The whole process happens in a 3-step process. The operators have to insert the protocol card into the system. They have to then place the cartridges into the system. As soon as the instrument is fed, it automatically purifies the nucleic acids and feeds them into the elution tubes. Finally, the operators can take out the highly pure samples present in the microcentrifuge tubes. That is how simple it is to use the instrument.

2. Flexibility: 

Not necessary that convenient usage is followed by flexibility. But in this case, these two features go together for the EZ1 systems. Qiagen provides numerous protocols to cater to different applications, including DNA and RNA purification, viral nucleic acids’ purification, etc. These machines are capable of purifying around 1-14 samples within 20 minutes. Moreover, the users can operate the machine using the keypad. Its Vacuum Fluorescent Display presents all the instructions related to the workflow, easing the usage. The system throughput can be increased up to 56 samples per run, by connecting it to an external computer.

3. Traceability and Standardization: 

The Advanced XL systems come with barcode readers to enable complete tracking of all the reagents and samples. These systems also have the facility to enter the notes and information related to assay identification. In case of expiry, the systems send warning alerts to notify the users. These systems are fed with the entire information related to the workflow, including documentation data, maintenance procedures, etc. Moreover, the users can easily transfer the data to a computer or a printer connected within the system’s network. Its LIMS can be used to process the entire information whenever needed.

The EZ1 Advanced XL instrument uses proven EZ1 Kits for the purification of DNA, RNA, and viral nucleic acids from a wide range of starting materials. Purified nucleic acids are ready for immediate use in downstream applications. The combination of an easy-to-use instrument, with error-free protocol selection and worktable setup, and prefilled, sealed reagent cartridges makes nucleic acid purification easy.


  • Qiagen EZ1 Advanced XL.
  • Dell Latitude i7 running Windows 10 Pro with EZ1 Software.
  • All communication and power cables.

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